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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44bc4e8546aa1f454ba0e29c7ec161c1d78a08574ce451ade8554f0ca04c8fe2' 
  AND token = 'SASs3sedPUqInxtXRjhFU2TZPg+IES+wRnrBGCXq/Ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}