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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12a1a9c2b562dd0039d0cc3b287e1aa57c9e2c9d9d269c701ceac17417b4adec' 
  AND token = 'NTHnmg27cBh4/IdNM0ZPUppSEm+hxOxtVqE+YgOdzV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}