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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d272b4a70da2f57dc4dd8c4f0a0833ab988e630dfcd86cd6c20984e383e1cae' 
  AND token = 'wKEmuy5tDROqKpVHxX4oT58S1E79xSh3z69YGUFmA08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}