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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6148ae61e71f961febd3e9d8c3734e0c5a750eb6215306e7230825770c70ec15' 
  AND token = '6uRl2QuSTMQ4M2Rb6/e8EGMhF6hhpBcXPH8GR78yao0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}