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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d280cb5aa953228fc4d5e69b5ac11b1f7142b87fcd525af838f5cadbedc524f' 
  AND token = 'rx6eSPhsfPnA9AY8bR/4ykWugTpqNVmaw1Ps0Hnhtbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}