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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8ad7ceae07d13d9afabdf748fc66ddb53840d24d6f0db18055b51d08ccd07d3' 
  AND token = 'T9I6VDqE/3lkpdC07odCfZy+RkOQlPtSaSYDk+Dy56c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}