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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ae21468f7415a8f5c1f100a4a2d8d7dc787563291310205eef0cc93b1721591' 
  AND token = 'nQVLQ2T7cASshUXhADRodb6mhOiF9ihf78c1YOV8NhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}