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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4843860cf2c2f2377c58d04086be7129081a3a601ac92021619a9f3150f8ef30' 
  AND token = 'js2dhuBGJGD2dCz7pwS74kPhO+dBGT9OsHm4HtS5aXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}