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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b192cfa80dad141608c0604e253eba0440d28df8352afb6d8788a38b3ee1292' 
  AND token = 'r5OW2o3Mw8EA4sY2qO5c5Ib/HOynjZo6FcWFA8nkaZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}