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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73c6a5b81c82b78805ee72dbfdc7251747be2bf3bd26d22d5f3529f69256e81d' 
  AND token = '2FbFop2VNonYTdVQ6LAz86HOdArEfI3VoGS43aieYig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}