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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c76ccc180eece7dddaadc250ab46d86422544c8b4cb840e11aa0589d751a89dd' 
  AND token = 'HUXgTC4Q0y7uY5vwlMR0q1DeDjDaCbDBsglSsKWdDS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}