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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4f36410085682620221e2bef3fdb0396dbcbcf50bf3ae02cf81bb7de0f9509d' 
  AND token = 'iL0FBgL9jPKGIOHBx/t+Bbl3g3hUSkR0vLTvw/kMcPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}