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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '561c4ca850becec25da1cd7181b89f745f39e25781cf315e98e4b47727945f5d' 
  AND token = 'VkKewXggQqtf3wQxB61jnfgyflKbuvR3+fbVSEQ4x+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}