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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54910012f7255836291d1fe4ddaa670dd73e4f425e9ec14598df1b15b6ddf0d6' 
  AND token = 'pukTWEAC7LHI+LNDNMhDm1DGbyT2N10bc39zNvS1Z5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}