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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8260e8934c0fe7cc453abec2d0f36942c8b61cb56cd66c31cfdb5b989006dc25' 
  AND token = 'TOZzixfwwngH9oZTBalwE13BD9M//ZV9bSQAxOxBEyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}