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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2772878ef17822df5022733fbf678df48554f71d6a758057906cfebd7db275c3' 
  AND token = 'E2R+pAc9P05Yro0KQ/vCJ7Jom3EvTRaNRkuiEtL0ePU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}