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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e9de5124b5d9152a46252b7b733474db661ff8c9b86a9ce7298841fefba9c6' 
  AND token = '6KBYYxTm/IoPbc68B4uzlpY0yDx9Ya4f81ndwt4D98Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}