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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a0be72c8bcf2a9ca5441533bf0613f595ed0f0ff34b62d26e3370ddc4b183fb' 
  AND token = '4LffRdr1je1EKJrxwNT0tlXO9izCeyHT8pz+SE/sPkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}