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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd7b78a559c15b8c55d10c74f15929c6bb286b47b1f80133cf62f2b61a40f2eb' 
  AND token = 'cq7byKf+cTDP+/ozc6VDH2HEbhVGV9A2cRik8JEcCCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}