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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '851b02f0d1afc27ccb75dac49c92e8902d77dff35ce38dc9cb4453201694c652' 
  AND token = 'jePrjaS6lWkjaju7p4NBwzDDdY2e+2taY4eUmIuBh0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}