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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d20cf8ba8f9c52d063ee5884a1c42272c8ae213700a01589f1a2e96cfd03563' 
  AND token = '+IwkKZhMS3ujdPxXQEFCjQJTkrCNUpHMJ6gFeniCD00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}