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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c0324b73e5a3c3aa1e2364020ddcb49c4c062531d77af5a221daf4af9e9a647' 
  AND token = 'etykwH4yQATzsuyksJcA9hq88vANBT/e/q0Q0nZO6NE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}