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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24765dc8363ce86ef87e4d9c67fc86ce0572a16a64cb06a788c2c5a84015ae15' 
  AND token = 'k5pQQcBONTu1++N/o1Ha1eLL6JCyNpG9QtIX9oFfYqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}