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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '382c48ea99bc4d9a27486f4d1f9ec1c1f53ced458fca540fe2b4964d387289fe' 
  AND token = 'Xsvbb2ixyb7fv4oDFGc+c88vIOHpUMNYJuHAERXCMJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}