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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd526e5b3b2e5cec0d6e21abc4e49e8f7c03c2781742ab0a29fdae160749291b' 
  AND token = 'CdXMtdUeM2IG5D2C9DVreu1T+CxHhC98XRoEu56IHdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}