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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '427a09ebbf8dc23f91169042453818eac97a267705c6cdeb7962cafa4bd0b400' 
  AND token = 'iVQbV4x7mA//XAe1SMibD/34W4B1TX+rQqRIrCSLeA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}