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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b81abe495f2d3d56f30f9b6cec237d3c4c67e9f0249c7124c19c72845ec64cb' 
  AND token = 'XWfHbZ56fJaRz6p5vnHwlbCKA3TZJcgZ4BPrUM/O+kE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}