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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32649363e3e805a0a32f76f9d8619203062f7af5f3bcb33c35a1983e67c8fc03' 
  AND token = 'qiMZtg8r8eOZWLkUWvdPMQd609+GR+2W6DWSc3dGMaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}