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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a21430a791621dc315f21c0a43a16c4742f9d52b8f317dc9b6916bfaa650a547' 
  AND token = 'wA9bIF03mJuy1sCVTq4apsOnjmQDPyGOGDAGOelr0Fc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}