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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e2d69aa12b82add7b1d096417fe8023b7f98d394fc858006150663f60052182' 
  AND token = '8G0tJ1l3y7L8BIxWmw4yb1/M341E+gkmh1AzfDhI4cA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}