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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0e4dd1062d44a7f817c7dc8f4b9756de42613eccbd1f9972ee200d56cb05426' 
  AND token = 'HJizQvWkP78b+l1z+aENl6rJXWuBWkaDaOls405gq5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}