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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8f5157eecff4f6f4eaac76d4e93fa02a66307f199735a8afd553c5cb987b7c5' 
  AND token = 'VI7leWyqv6b9G/eIzlalUX8XHgGnEE+Lkg4gIvf9Uq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}