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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '260b51359b37c74ee83b7d45ab1513f3dba1fe755efbf0b2874571272cf10b09' 
  AND token = 'NkXG/aDyH3BX3Dk7gflsocB7429kYSlpeDPgyZaqPzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}