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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a00e4b67e94e43a156274f5cc3dabbcdd8cd3155a6d06589111891086dd5b557' 
  AND token = 'CWiE4IiA7OgNN5Ht2QJ4iyGUNLnht4GIlfz9xqPqDEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}