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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4504e9cc13d0883e635c0413640d13a94e876233b1e0ee1510d58cfcb6a5bd78' 
  AND token = '3AV/dwn1dqzmUJeylxSarN3zcb4PnSA6290pwIa5RdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}