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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce1f15b25149c9a0da0219390a045d315d25b47f8f878ecc905cad5a6a4e81b1' 
  AND token = 'UqbbEnUhGwHuRGnRLUDeO5vKd3kiaKpQGc40ka9+sf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}