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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6331a2ddb1eb9731b7ea9adb75761c2e329bb735bd81c36becc9569d5358f646' 
  AND token = 'oPNfIVj8Sr9cvdghbeztPYAjiKamSvY2hxOlKExeT+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}