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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44fa7ac0270f0106bbbf17359d683729c25e50e5f8d4d3503e0bb475a1e135aa' 
  AND token = '7FXNJqzY7Ikfn1Fbgo55dVtGYT6nFetzlv1xKmKGERA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}