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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '366b51ea4961af6160b33532c1df12dcdc81b7d532d3eea6393debb649c47a49' 
  AND token = 'Vtbnct1vxc1P7Hr3izye5GMOLQm/XzMnoCLYo3Xih7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}