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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d3e756b796a6e9f32340d3ebe74cb60c1a7eba57efa38952c511b15ca470852' 
  AND token = '6MUe0OMo/WoM4jLORAF3NAuu5ddCJqVt3LyD4Iko9pA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}