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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff99dbaf4f6ea6f1ff1dc22338db48d67dac1545155b8b8f7f4aeb2fe571fbcb' 
  AND token = 'pO0egzcZz1ZicGqQZ3vdT4z4uwj8avztBh8uOR2nTxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}