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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b54698a0efe3806b60c8eb6eb5c4d96573808c0eceb332bd7e1db6c7af714f2' 
  AND token = 'up+B6kpI7CvBZH9t0SGr9hDhFkFh0TCcY2oGyherkLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}