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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd78cf992cdc455973df00c687b60ebf17f6061480df600faa891486af0b65059' 
  AND token = 'nFqBeu5LfhDIXxMYUlUIvL0lItRkStI2X6W/BMtFwNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}