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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43d664754105023c84bc7a269fdfcf43edbaaa1387290f1dee32a4fc3932b57d' 
  AND token = 'Y1A9FglMdQV8P9mAVbopkQoV367o9bUMgX/d6Qs+NMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}