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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74b4219121627fe9a61dca8eda2bee01ec40d13826fbcc07687c3934fbcfd28c' 
  AND token = 'fhIutq6F2reYK8RVmgUvNZ3h7sr6qC/C7LU9F/F3Guk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}