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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48534e7a3c6ce219e5759561321e5252abb7c9a8a61a34c0f8bcb0a63cb0320d' 
  AND token = 'D/fc6yynMl8v0u5gpGKx/xhvc1sGOq/FYJ2oOdxeLSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}