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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd414d6cc4eec189a19cb03f015c1237c6375cfc7752ceb5a825d77b651abb4f0' 
  AND token = 'Neq6Z00WyuXgSB49aK9FABEoYVSiTqYZ5nax8IdFwl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}