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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2213044e6c4733f16cb5be396a5e8d2d3c8f4863cb321f3daf5fbaede113c038' 
  AND token = 'KQJEfW75mvbv8gdcjYXQfNixNQwj59uxu56nTVU4lVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}