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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc35157e4d61ee6f8ee6324f5eff31b84ab9db115e3bf83f65f3dccb730facaa' 
  AND token = 'WC2VVBTB0cCaOLqA9n2GkKQL3RrAKSvFrWNe2Rdf+ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}