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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e87141a30b29d9304cec29e6235bab10efeb7f184f2283e6895e115679864ed3' 
  AND token = 'ij+QySDEHMjzVuEboNJ/L1UqBrMAoXsrAsxKnNtfJpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}